Evaluation of Three Commercial Serological Tests with Different Methodologies to Assess Helicobacter Pylori Infection

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1999 Nov 24

PMID 10565949

Citations 9

Authors

A van der Ende

R W van der Hulst

P Roorda

G N Tytgat

J Dankert

Affiliations

Soon will be listed here.

Abstract

The sera of 142 Helicobacter pylori-positive and 32 H. pylori-negative patients were assessed by a desktop test (QuickVue), an enzyme-linked immunosorbent assay (ELISA) (HM-CAP), and a solid-phase, two-step chemiluminescent enzyme immunoassay (Immulite). These tests yielded sensitivities of 97, 97, and 91% and specificities of 97, 94, and 100%, respectively. In conclusion, the desktop test and the ELISA are more sensitive than the chemiluminescent enzyme immunoassay (P < 0.05). The chemiluminescent enzyme immunoassay has the advantage that it is fully automated.

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