Hypofluorescent Spots on Indocyanine Green Angiography at the Recovery Stage in Multiple Evanescent White Dot Syndrome

Purpose: To evaluate the fundus lesions in a young woman.

Methods: Visual function, ophthalmoscopy, electrophysiology, fluorescein angiography, and indocyanine green angiography were performed.

Results: A 24-year-old woman had decreased visual acuity (0.2), granularity in the macula, and multiple yellow-white patches in the fundus, reduced a wave on electroretinography, hyperfluorescence on fluorescein angiography, and hypofluorescence on indocyanine green angiography in the left eye. When visual acuity improved to 1.0, the white dots disappeared ophthalmoscopically, and fluorescein angiography showed normal findings. Hypofluorescent spots were found, however, on indocyanine green angiography.

Conclusion: It is possible that signs of multiple evanescent white dot syndrome may remain longer during examination by indocyanine green angiography than by visual function, ophthalmoscopy, or fluorescein angiography.