Cadherins and Their Connections: Adhesion Junctions Have Broader Functions

Overview

Journal Curr Opin Cell Biol

Publisher Elsevier

Specialty Cell Biology

Date 1999 Oct 6

PMID 10508659

Citations 63

Authors

M S Steinberg

P M McNutt

Affiliations

Soon will be listed here.

Abstract

Cadherins - a family of cell-cell adhesion molecules - are linked to the actin cytoskeleton via intervening proteins. Recent results address molecular explanations for observed cadherin behavior, point to signals that regulate adhesion by modulating elements of the cadherin-associated complex, challenge the belief that different cadherins generally cannot cross-adhere, and highlight instructive roles for cadherins in cell signaling and differentiation.

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