Recombinant Baculoviruses As Expression Vectors for Insect and Mammalian Cells

Overview

Journal Curr Opin Biotechnol

Publisher Elsevier

Specialty Biotechnology

Date 1999 Oct 6

PMID 10508635

Citations 30

Authors

T A Kost

J P Condreay

Affiliations

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Abstract

Baculovirus expression vectors are widely used for expressing heterologous proteins in cultured insect cells. Recent advances include further development of the system for production of multi-subunit protein complexes, co-expression of protein-modifying enzymes to improve heterologous protein production, and additional applications of baculovirus display technology. The application of modified baculovirus vectors for gene expression in mammalian cells continues to expand.

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