Lymphatic Absorption of Phytosterol Oxides in Rats

Overview

Journal Lipids

Specialty Biochemistry

Date 1999 Jul 16

PMID 10405969

Citations 1

Authors

A Grandgirard

J P Sergiel

M Nour

C Ginies

Affiliations

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Abstract

Two of the main classes of oxyphytosterols (7-keto and epoxides) were synthesized from sitosterol and campesterol and given to mesenteric duct-cannulated adult male rats. Lymph was collected during 24 h and was analyzed for oxysterols. The results showed that the lymphatic recovery of the phytosterol oxides was low: 4.7% of the given dose for epoxy derivatives and 1.5% for 7-keto compounds. The campesterol oxides presented a better absorption than the sitosterol oxides. During the process of absorption, the epoxyphytostanols were also partly transformed in campestanetriol and stigmastanetriol.

Citing Articles

Phytosterol oxidation products (POP) in foods with added phytosterols and estimation of their daily intake: A literature review.

Lin Y, Knol D, Trautwein E Eur J Lipid Sci Technol. 2016; 118(10):1423-1438.

PMID: 27812313 PMC: 5066650. DOI: 10.1002/ejlt.201500368.

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