Use of Recombinant Human Cardiac Troponin T for Standardization of Third Generation Troponin T Methods

Overview

Journal Scand J Clin Lab Invest Suppl

Specialty Pathology

Date 1999 Jul 2

PMID 10389211

Citations 18

Authors

K Hallermayer

D Klenner

R Vogel

Affiliations

Soon will be listed here.

Abstract

The Elecsys Troponin T third generation assay uses recombinant human cardiac troponin T as standard material. The new assay has a linear calibration curve. Thus, linearity problems observed with the second generation assay have been eliminated. The assay has high precision, especially at the low end of measuring range (inter-assay CV < 10% at 0.1 microgram/L). The new standardization does not change the cut-off value of 0.1 microgram/L. The use of recombinant human cardiac troponin T as standard material enables a reproducible and reliable standardization of troponin T assays.

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