Ductus Venosus Blood Velocity in Persistent Pulmonary Hypertension of the Newborn

Overview

Journal Arch Dis Child Fetal Neonatal Ed

Specialties Gynecology & Obstetrics
Pediatrics

Date 1999 Jun 22

PMID 10375360

Citations 2

Authors

D Fugelseth

T Kiserud

K Liestol

A Langslet

R Lindemann

Affiliations

Soon will be listed here.

Abstract

Aims: To investigate the ductus venosus flow velocity (DVFV) in infants with persistent pulmonary hypertension of the newborn (PPHN); to evaluate the DVFV pattern as a possible diagnostic supplement in neonates with PPHN and other conditions with increased right atrial pressure.

Methods: DVFV was studied in 16 neonates with PPHN on days 1-4 of postnatal life using Doppler echocardiography. DVFV was compared with that in mechanically ventilated neonates with increased intrathoracic pressure, but without signs of PPHN (n=11); with neonates with congenital heart defects resulting in right atrial pressure (n=6); and with preterm neonates without PPHN (n=46); and healthy term neonates (n=50).

Results: Infants with PPHN and congenital heart defects with increased right atrial pressure were regularly associated with an increased pulsatile pattern and a reversed flow velocity in ductus venosus during atrial contraction. A few short instances of reversed velocity were also noted in normal neonates before the circulation had settled during the first day after birth.

Conclusions: A reversed velocity in the ductus venosus during atrial contraction at this time signifies that central venous pressure exceeds portal pressure. This negative velocity deflection is easily recognised during Doppler examination and can be recommended for diagnosing increased right atrial pressure and PPHN.

Citing Articles

Case Report: Clinical Features of Congenital Portosystemic Shunts in the Neonatal Period.

Xu S, Zhang P, Hu L, Zhou W, Cheng G Front Pediatr. 2021; 9:778791.

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Patent Ductus Venosus and Congenital Heart Disease: A Case Report and Review.

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