A Relative Power Table for Nested Matched Case-control Studies

Overview

Journal Occup Environ Med

Specialties Environmental Health
Occupational Medicine

Date 1999 May 26

PMID 10341749

Citations 12

Authors

D Pang

Affiliations

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Abstract

Objective: To calculate relative powers for nested case-control studies for different values of both relative risk and numbers of controls per case, given a fixed number of cases available for analysis.

Methods: Algebraic and numerical methods.

Results: In nested case-control studies, statistical power is a function of relative risk, rarity of exposure, number of case-control sets, and the number of controls per case.

Conclusion: The dictum that sufficient power will be obtained in a nested case-control study by selecting only four controls per case cannot be sustained. Appropriate numbers need to be calculated for specific studies.

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