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Hepatocellular Carcinoma

Overview
Journal Lancet
Publisher Elsevier
Specialty General Medicine
Date 1999 Apr 27
PMID 10217098
Citations 126
Authors
D F Schafer
M F Sorrell
Affiliations
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Abstract

Hepatocellular carcinoma (HCC) for most patients is a terminal complication of chronic inflammatory and fibrotic liver disease. With regrettably few exceptions, treatment is largely palliative, and long-term survival is rare. However, the major causes of HCC worldwide are known and preventable. Hepatitis B and C exist only in man; the viruses have no known non-human reservoirs. Transmission of the viruses can be interrupted by vaccination against hepatitis B virus infection and improvements in medical techniques for hepatitis C, for which no vaccine has yet been developed.

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