Combinatorial Approaches to Materials Discovery
Overview
Affiliations
Using a mixture of scientific intuition, iteration and serendipity, combinatorial materials science is an approach to the discovery and study of new materials that combines high-speed chemical synthesis, high-throughput screening and high-capacity information processing to create, analyse and interpret large numbers of new and diverse material compositions. Technology has now been developed that makes this powerful integration possible. The classes of materials under investigation include catalysts, luminescent, optical, magnetic and dielectric materials, and structural polymers.
Synthesis at the Interface of Chemistry and Biology.
Schultz P Acc Chem Res. 2024; 57(18):2631-2642.
PMID: 39198974 PMC: 11443489. DOI: 10.1021/acs.accounts.4c00320.
Accelerated Synthesis of Ordered Mesoporous Carbons Using Plasma.
Griffin A, Chen G, Robertson M, Wang K, Xiang Y, Qiang Z ACS Omega. 2023; 8(17):15781-15789.
PMID: 37151511 PMC: 10157878. DOI: 10.1021/acsomega.3c01523.
Unosson E, Morgenstern M, Engqvist H, Welch K J Mater Sci Mater Med. 2016; 27(3):49.
PMID: 26758896 DOI: 10.1007/s10856-015-5662-5.
Small-molecule peptides inhibit Z alpha1-antitrypsin polymerization.
Chang Y, Mahadeva R, Chang W, Lin S, Chu Y J Cell Mol Med. 2009; 13(8B):2304-2316.
PMID: 19120695 PMC: 6529975. DOI: 10.1111/j.1582-4934.2008.00608.x.
Use of combinatorial chemistry to develop photocurable thermoplastic polyurethane elastomers (TPUs).
Heras J, Falco J, Borros S, Borrell J, Nonell S Mol Divers. 2004; 6(2):157-63.
PMID: 14761165 DOI: 10.1023/b:modi.0000006859.46262.f5.