Phosphorylcholine: Friend or Foe of the Immune System?

Overview

Journal Immunol Today

Specialty Allergy & Immunology

Date 1999 Apr 22

PMID 10203703

Citations 53

Authors

W Harnett

M M Harnett

Affiliations

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Abstract

Phosphorylcholine (PC) is a structural component of a variety of prokaryotic and eukaryotic pathogens. In some cases, PC in infectious agents can benefit the infected host due to its targeting by both the innate and adaptive immune responses. However, as discussed here, PC exhibits a surprising range of immunomodulatory properties that might be to the detriment of the host.

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