Survey of Antibiotic Resistance Among Enterococci in North Rhine-Westphalia, Germany

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 1999 Apr 16

PMID 10203546

Citations 4

Authors

R R Reinert

G Conrads

J J Schlaeger

G Werner

W Witte

R Lutticken

I Klare

Affiliations

Soon will be listed here.

Abstract

A surveillance study on antibiotic resistance of enterococcal isolates (n = 730) was carried out in North Rhine-Westphalia, Germany, in 1997. Resistance rates to ampicillin (7.4%), high-level gentamicin (15.0%), high-level streptomycin (27.9%), ciprofloxacin (37.9%), vancomycin (1.5%), and teicoplanin (1.5%) were determined. All vancomycin-resistant enterococci (VRE) carried the vanA gene. SmaI and ApaI macrorestriction patterns indicated an intra- and interhospital spread of VRE.

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References

Facklam R, Collins M . Identification of Enterococcus species isolated from human infections by a conventional test scheme. J Clin Microbiol. 1989; 27(4):731-4. PMC: 267406. DOI: 10.1128/jcm.27.4.731-734.1989. View

Lutticken R, KUNSTMANN G . Vancomycin-resistant Streptococcaceae from clinical material. Zentralbl Bakteriol Mikrobiol Hyg A. 1988; 267(3):379-82. DOI: 10.1016/s0176-6724(88)80054-3. View

Molinas C, Arthur M, Courvalin P . The VANA glycopeptide resistance protein is related to D-alanyl-D-alanine ligase cell wall biosynthesis enzymes. Mol Gen Genet. 1990; 224(3):364-72. DOI: 10.1007/BF00262430. View

Moellering Jr R . Emergence of Enterococcus as a significant pathogen. Clin Infect Dis. 1992; 14(6):1173-6. DOI: 10.1093/clinids/14.6.1173. View

Klare I, Heier H, Claus H, Witte W . Environmental strains of Enterococcus faecium with inducible high-level resistance to glycopeptides. FEMS Microbiol Lett. 1993; 106(1):23-9. DOI: 10.1111/j.1574-6968.1993.tb05930.x. View

Woodford N, Morrison D, Cookson B, George R . Comparison of high-level gentamicin-resistant Enterococcus faecium isolates from different continents. Antimicrob Agents Chemother. 1993; 37(4):681-4. PMC: 187734. DOI: 10.1128/AAC.37.4.681. View

Eliopoulos G . Increasing problems in the therapy of enterococcal infections. Eur J Clin Microbiol Infect Dis. 1993; 12(6):409-12. DOI: 10.1007/BF01967433. View

Clark N, Cooksey R, Hill B, Swenson J, Tenover F . Characterization of glycopeptide-resistant enterococci from U.S. hospitals. Antimicrob Agents Chemother. 1993; 37(11):2311-7. PMC: 192384. DOI: 10.1128/AAC.37.11.2311. View

Devriese L, Pot B, Collins M . Phenotypic identification of the genus Enterococcus and differentiation of phylogenetically distinct enterococcal species and species groups. J Appl Bacteriol. 1993; 75(5):399-408. DOI: 10.1111/j.1365-2672.1993.tb02794.x. View

10.

Bates J, Jordens J, Griffiths D . Farm animals as a putative reservoir for vancomycin-resistant enterococcal infection in man. J Antimicrob Chemother. 1994; 34(4):507-14. DOI: 10.1093/jac/34.4.507. View

11.

Klare I, Heier H, Claus H, Reissbrodt R, Witte W . vanA-mediated high-level glycopeptide resistance in Enterococcus faecium from animal husbandry. FEMS Microbiol Lett. 1995; 125(2-3):165-71. DOI: 10.1111/j.1574-6968.1995.tb07353.x. View

12.

Tenover F, Arbeit R, Goering R, Mickelsen P, Murray B, Persing D . Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995; 33(9):2233-9. PMC: 228385. DOI: 10.1128/jcm.33.9.2233-2239.1995. View

13.

Miele A, Bandera M, Goldstein B . Use of primers selective for vancomycin resistance genes to determine van genotype in enterococci and to study gene organization in VanA isolates. Antimicrob Agents Chemother. 1995; 39(8):1772-8. PMC: 162824. DOI: 10.1128/AAC.39.8.1772. View

14.

Klare I, Heier H, Claus H, Bohme G, Marin S, SELTMANN G . Enterococcus faecium strains with vanA-mediated high-level glycopeptide resistance isolated from animal foodstuffs and fecal samples of humans in the community. Microb Drug Resist. 1995; 1(3):265-72. DOI: 10.1089/mdr.1995.1.265. View

15.

Wallrauch C, Elsner E, Milatovic D, Cremer J, Braveny I . [Antibiotic resistance of enterococci in Germany]. Med Klin (Munich). 1997; 92(8):464-8, 505. DOI: 10.1007/BF03044913. View

16.

Werner G, Klare I, Witte W . Arrangement of the vanA gene cluster in enterococci of different ecological origin. FEMS Microbiol Lett. 1997; 155(1):55-61. DOI: 10.1111/j.1574-6968.1997.tb12685.x. View

17.

Claus H, Cuny C, Pasemann B, Witte W . A database system for fragment patterns of genomic DNA of Staphylococcus aureus. Zentralbl Bakteriol. 1998; 287(1-2):105-16. DOI: 10.1016/s0934-8840(98)80154-0. View

18.

Murray B . The life and times of the Enterococcus. Clin Microbiol Rev. 1990; 3(1):46-65. PMC: 358140. DOI: 10.1128/CMR.3.1.46. View