Cryptococcosis in the Northern Territory

This report represents a review of cryptococcosis in the Northern Territory from 1957 to 1975. There were 26 cases over a 19-year period; 25 of these were in full-blooded Aborigines. The disease occurred throughout the rural areas of the Territory as isolated cases. There were 24 cases of cryptococcal meningitis and only two with solitary lung involvement. The overall mortality was 50%. In all five untreated cases the disease was fatal. There were eight deaths among the 20 patients receiving chemotherapy, a mortality of 40%. Lung resection was performed in six cases of localized pulmonary cryptococcosis. The outcome for these was excellent.