Lymphocyte Locomotion III. Ultrastructural Studies of the Lymphocyte Traffic over the Postcapillary Venules of Rat Lymph Nodes

The direction of lymphocytes with amoeboid movement configuration (AMC) was evaluated by means of electron microscopy of ultrathin sections of post-capillary high-endothelium venules (HE-venules) from rat lymph nodes. Out of 104 lymphocytes, 68 lymphocytes appeared to be on their way towards the lumen of the HE-venule and 36 lymphocytes appeared to be moving away from the venular lumen at the moment of fixation. This difference, which was statistically significant (p=0.0024), is thought to reflect the relative size of the migration stream of lymphocytes at the moment of fixation.