Electrophoretically Silent Alleles in a Finite Population
Overview
Authors
Affiliations
The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.
Population genetic characteristics of the D1S80 locus in seven human populations.
Deka R, DeCroo S, Jin L, McGarvey S, Rothhammer F, Ferrell R Hum Genet. 1994; 94(3):252-8.
PMID: 8076940 DOI: 10.1007/BF00208279.
Bhatia K, Blake N, Serjeantson S, Kirk R Am J Hum Genet. 1981; 33(1):112-22.
PMID: 7468589 PMC: 1684889.
Composite stepwise mutation model under the neutral mutation hypothesis.
Takahata N J Mol Evol. 1980; 15(1):13-20.
PMID: 6928979 DOI: 10.1007/BF01732579.
Simulation results with stepwise mutation model and their interpretations.
Chakraborty R J Mol Evol. 1977; 9(4):313-22.
PMID: 894733 DOI: 10.1007/BF01796093.
Estimating total genic diversity in the house mouse.
Bonhomme F, Selander R Biochem Genet. 1978; 16(3-4):287-97.
PMID: 678296 DOI: 10.1007/BF00484085.