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HLA-B27 Antigen in Diagnosis of Atypical Seronegative Inflammatory Arthropathy

Overview
Journal Ann Rheum Dis
Specialty Rheumatology
Date 1976 Dec 1
PMID 1008621
Citations 9
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Abstract

Eighteen patients with an inflammatory pauciarticular peripheral arthropathy not typical of any known entity showed an asymmetrical pattern of disease, with a predilection for the lower extremities. Destructive joint changes and deformities were absent (mean follow-up 10 years). Although spondylitis and sacroiliitis were absent on x-rays, HLA-B27 antigen was found in 8 patients (44%). This antigen and similar joint symptoms are also found in other forms of arthritis.

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