Tetrahymena Pyriformis: a Tool for Toxicological Studies. A Review

Overview

Journal Chemosphere

Specialties Biology
Chemistry
Environmental Health

Date 1999 Mar 10

PMID 10070737

Citations 30

Authors

M P Sauvant

D Pepin

E Piccinni

Affiliations

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Abstract

Among protozoa, Tetrahymena pyriformis is the most commonly ciliated model used for laboratory research. After a brief description of the morphology and biology of Tetrahymena pyriformis, this article focuses on the most important and recent investigations performed with this species in toxicology and ecotoxicology. The methodological features of its culture, and main tests, based on cell growth rate, biochemical markers, behavioral changes and motility, are discussed. Examples of xenobiotics (organic and inorganic substances, pharmaceutical drugs, water pollutants) tested with Tetrahymena pyriformis are also given.

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