Chemotactic Response of Leukocytes to Cord Factor (trehalose-6,6'-dimycolate)

Overview

Journal J Natl Cancer Inst

Publisher Oxford University Press

Specialty Oncology

Date 1976 Dec 1

PMID 1003563

Citations 7

Authors

I Ofek

A Bekierkunst

Affiliations

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Abstract

Cord factor (trehalose-6,6'-dimycolate), a glycolipid extractable from myocobacteria, was chemotactic for peritoneal cells of mice at concentrations from 5 to 25 mug/ml medium, as well as for peripheral white blood cells of mice and humans. At higher concentrations, presumably only macrophages were attracted.

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