Development and Cytodifferentiation of the Rabbit Pars Intermedia. II. Neonatal to Adult

Overview

Journal J Anat

Specialty Anatomy & Histology

Date 1976 Nov 1

PMID 1002611

Citations 7

Authors

P Chatterjee

Affiliations

Soon will be listed here.

Abstract

Material from pars intermedia obtained from rabbits ranging from the second week post-partum to the adult stage, and including specimens from pregnant animals, was studied. The rate of cell division became greatly reduced early in postnatal) development. The commonest type of cell (the pars intermedia-glandular cell) becomes increasingly PAS-positive during the early stages of development. Although by 35 days differentiation of all the ACT-type cells is complete, the pars intermedia-glandular cells take as long as 53 days to mature. The epithelioid border of the hypophysial cleft persists throughout life, commonly containing dark cells. A ciliary fringe frequently appears in neonates and persists in pregnancy. Possible functions of such cilia are discussed. Throughout development the fine structure of the vasculature was studied. Secretory granules resembling those within the cells were seen in and around the blood vessels, and the mode of endocrine secretion in the pars intermedia tissue is discussed. The pars intermedia-glandular cells of the pregnant rabbits appeared hyperactive. The functional significance of the mammalian pars intermedia is discussed.

Citing Articles

Ontogenesis of the rabbit pituitary intermediate lobe. An ultrastructural and immunocytochemical study.

Schimchowitsch S, Plante M, Klein M, Stoeckel M Anat Embryol (Berl). 1993; 187(1):87-97.

PMID: 8381621 DOI: 10.1007/BF00208199.

Follicles and related structures in the pars intermedia of the adenohypophysis of the jird (Meriones unguiculatus).

Bhattacharjee D, Chatterjee P, HOLMES R J Anat. 1980; 130(Pt 1):63-7.

PMID: 7364664 PMC: 1233109.

Ultrastructure of the pars intermedia of the adult sheep hypophysis.

Perry R, Robinson P, RYAN G Cell Tissue Res. 1981; 217(1):211-23.

PMID: 7249044 DOI: 10.1007/BF00233839.

Ultrastructure of the pars intermedia of the developing sheep hypophysis.

Perry R, Robinson P, RYAN G Cell Tissue Res. 1982; 224(2):369-81.

PMID: 7105139 DOI: 10.1007/BF00216880.

The embryological development and cytodifferentiation of the anterior pituitary in the marsupial, Isoodon macrourus.

Hall L, Hughes R Anat Embryol (Berl). 1985; 172(3):353-63.

PMID: 2415023 DOI: 10.1007/BF00318984.

References

Harris G . The blood vessels of the rabbit's pituitary gland, and the significance of the pars and zona tuberalis. J Anat. 1947; 81(Pt 4):343-51. PMC: 1272813. View

Salazar H, Peterson R . MORPHOLOGIC OBSERVATIONS CONCERNING THE RELEASE AND TRANSPORT OF SECRETORY PRODUCTS IN THE ADENOHYPOPHYSIS. Am J Anat. 1964; 115:199-215. DOI: 10.1002/aja.1001150202. View

Salazar H . THE PARS DISTALIS OF THE FEMALE RABBIT HYPOPHYSIS: AN ELECTRON MICROSCOPIC STUDY. Anat Rec. 1963; 147:469-97. DOI: 10.1002/ar.1091470404. View

Farquhar M . Origin and fate of secretory granules in cells of the anterior pituitary gland. Trans N Y Acad Sci. 1961; 23:346-51. DOI: 10.1111/j.2164-0947.1961.tb01361.x. View

Farquhar M . Fine structure and function in capillaries of the anterior pituitary gland. Angiology. 1961; 12:270-92. DOI: 10.1177/000331976101200704. View

SHIZUME K, LERNER A . Determination of melanocyte-stimulating hormone in urine and blood. J Clin Endocrinol Metab. 1954; 14(12):1491-510. DOI: 10.1210/jcem-14-12-1491. View

Cameron E, Foster C . Some light- and electron-microscopical observations on the pars intermedia of the pituitary gland of the rabbit. J Endocrinol. 1971; 49(3):479-85. DOI: 10.1677/joe.0.0490479. View

Dahl H . On the cilium cell relationship in the adenohypophysis of the mouse. Z Zellforsch Mikrosk Anat. 1967; 83(2):169-77. DOI: 10.1007/BF00362398. View

Chatterjee P . Ultrastructural studies on the development of the nerve supply in the rabbit pars intermedia. Cell Tissue Res. 1974; 152(1):113-28. DOI: 10.1007/BF00224214. View

10.

Schechter J . The cytodifferentiation of the rabbit pars distalis: an electron microscopic study. Gen Comp Endocrinol. 1971; 16(1):1-20. DOI: 10.1016/0016-6480(71)90202-4. View

11.

Howe A . The mammalian pars intermedia: a review of its structure and function. J Endocrinol. 1973; 59(2):385-409. DOI: 10.1677/joe.0.0590385. View

12.

Chatterjee P . The effect of culture on ultrastructure of dissociated rabbit adenohypophysial cells. J Anat. 1976; 121(Pt 2):241-58. PMC: 1231797. View

13.

Amat P, Boya J . Ultrastructural observations on the genesis and extrusion of secretory granules in the adenohypophysis. Acta Anat (Basel). 1973; 86(1):44-52. DOI: 10.1159/000144107. View

14.

Chatterjee P . Development and cytodifferentiation of the rabbit pars intermedia. I. Fetal and perinatal stages. Cell Tissue Res. 1975; 164(4):481-501. DOI: 10.1007/BF00219940. View

15.

Sano M, Sasaki F . Embryonic development of the mouse anterior pituitary studied by light and electron microscopy. Z Anat Entwicklungsgesch. 1969; 129(3):195-222. DOI: 10.1007/BF00519088. View

16.

Vincent D, KUMAR T . Electron microscopic studies on the pars intermedia of the ferret. Z Zellforsch Mikrosk Anat. 1969; 99(2):185-97. DOI: 10.1007/BF00342220. View

17.

Dingemans K . The relation between cilia and mitoses in the mouse adenohypophysis. J Cell Biol. 1969; 43(2):361-7. PMC: 2107863. DOI: 10.1083/jcb.43.2.361. View

18.

Tixier-Vidal A, Picart R . [Quantitative study by radioautography and electron microscopy of the utilization of DL-leucine-H3 by duck hypophyseal cells in organ culture]. J Cell Biol. 1967; 35(3):501-19. PMC: 2107155. DOI: 10.1083/jcb.35.3.501. View

19.

KAGAYAMA M . The follicular cell in the pars distalis of the dog pituitary gland: an electron microscope study. Endocrinology. 1965; 77(6):1053-60. DOI: 10.1210/endo-77-6-1053. View